1-Propyl -1H-pyrazole-4-carboxylic acid is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Chemical formula: C9H10N2O2
-Molecular weight: 178.19g/mol
-Appearance: White solid
-Melting point: about 150-155°C
-Solubility: Slightly soluble in water, soluble in organic solvents such as chloroform, dimethyl sulfoxide, etc.
Use:
- 1-propyl -1H-pyrazole-4-carboxylic acid is commonly used as intermediates and reagents in organic synthesis
-It can be used to synthesize a variety of drugs, polymers and dyes and other organic compounds
-In the field of medicine, it can be used to synthesize anti-inflammatory, anti-tumor and anti-infective drugs
Preparation Method:
The preparation method of 1-propyl-1H-pyrazole-4-carboxylic acid can be achieved by the following steps:
1. Acetone reacts with tert-butyl acetate to give 1-propyl -1H-pyrazole-4-methanol.
2. Esterification of 1-propyl -1H-pyrazole-4-methanol with acid to give 1-propyl -1H-pyrazole-4-carboxylic acid.
3. Finally, 1-propyl -1H-pyrazole-4-carboxylic acid was subjected to a hydrolysis reaction to obtain 1-propyl -1H-pyrazole-4-carboxylic acid.
Safety Information:
- 1-propyl -1H-pyrazole-4-carboxylic acid is a chemical, should follow the appropriate safety procedures.
-During use and storage, keep it away from fire and high temperature, and store it in a sealed container.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing during operation.
-such as accidental contact with skin or eyes, should immediately rinse with plenty of water, and timely medical treatment.
-When disposing of waste, follow local environmental regulations and handle or dispose of it properly.